Change of HeART: Cardiovascular Implications of Assisted Reproductive Technology

Cardiovascular disease is the leading cause of death in women, and may manifest differently, part related to sex-specific cardiovascular risk factors. In females, assisted reproductive technologies (ART) are commonly used treat infertility, utilize controlled ovarian stimulation involving administration exogenous sex hormones. ART, especially stimulation, have been associated with an increased pregnancy short-term risk, though long-term implications these treatments individuals treated ART their offspring remain unclear. This review endeavors provide a comprehensive examination what known about relationship between outcomes for females as well offspring, recommendations future research. Novel insights into female-specific factors critical reduce disproportionate burden Canadian women. has revolutionized medicine, offering hope millions infertility worldwide, further understanding this important factor urgently warranted.